Vascupaint™ lead-free silicone injection compounds fill and opacify microvasculature structures and other spaces within non-surviving animals for micro-CT imaging or visual inspection with brightfield microscopy following alcohol based tissue clearing. Once injected, the Vascupaint mixture obtained by mixing the kit components undergoes a curing process, forming a precise three-dimensional cast of the vasculature and offering a detailed representation for analysis. Available in a variety of radiopaque colors and a clear option, Vascupaint allows for flexibility in visualization. Its lead-free composition ensures safety and compliance while providing complete filling and minimal shrinkage, resulting in vivid, optically cleared specimens ideal for detailed microcirculation studies. Color diversity further aids in delineating the circulatory tree, facilitating microscopic examination and photographic illustration. The injection compounds are available in two di?erent colors including yellow (SKU# MDL-121) for micro-CT imaging and green (SKU# MDL-122) for NIR or SWIR ?uorescence imaging as well as clear (SKU# MDL-123) for your custom preparations. Other colors are available upon request. Kit includes 200ml bottle of silicone (Green, Yellow, Lime, Blue, Red or Clear), 200ml bottle of diluent, and 20ml bottle of catalyst. Brain organs were harvested following perfusion with MediLumine's Vascupaint™ silicone injection compound containing X-ray attenuating bismuth pigments. Courtesy of Dr. Sean Marrelli (UT Health) and Bruker Preclinical Imaging (Billerica, MA). The 3D reconstructed images were obtained from microCT images acquired with scans at a resolution of 6 microns on a SkyScan 1276 imaging system. See picture below
