Pathology of the Mouse
Edited by Robert Maronpot
 

Description
The mouse is an up-and-coming research animal and is heavily utilized in toxicological testing. The mouse is the least costly of the rodents and the relative ease with which transgenic research can be conducted makes it a desirable animal model. An outstanding team of pathologists, headed by Dr. Robert Maronpot at the National Institute of Environmental Heath Sciences, provides a comprehensive survey of mouse pathology. This book is both a reference and atlas in that it covers all systems of the body and is heavily illustrated. Pathology of the Mouse is an indispensable reference for pathologists and biomedical scientists. Each pathologist should have a copy within arm's reach!

Detailed Contents

History of the B6C3F1 Mouse - GN Rao & GA Boorman

Growth, Body Weight Patterns and Life Span of the B6C3F1 Mouse - GN Rao

The Teeth - PH Long & JR Leininger

Oral Cavity, Esophagus and Stomach - JR Leininger, MP Jokinen, CA Dangler & LO Whiteley

Salivary, Harderian and Lacrimal Glands - S Botts, M Jokinen, E Gaillard, MR Elwell & PC Mann

Small and Large Intestine, and Mesentery - CC Shackelford & MR Elwell

Liver and Gallbladder - T Harada, A Enomoto, GA Boorman & RR Maronpot

Exocrine and Endocrine Pancreas - GA Boorman & RC Sills

Kidney - JC Seely

Ureter, Urinary Bladder, and Urethra - ET Gaillard

Nose, Larynx, and Trachea - RA Herbert & JR Leininger

Lungs, Pleura, and Mediastinum - D Dixon, RA Herbert, RC Sills & GA Boorman

Thymus, Spleen, and Lymph Nodes - JM Ward, PC Mann, H Morishima & CH Frith

Heart, Blood and Lymphatic Vessels - MR Elwell & JF Mahler

The Male Reproductive Tract - A Radovsky, K Mitsumori & R Chapin

Ovary, Oviduct, Uterus, Cervix and Vagina - B Davis, D Dixon & R Herbert

The Nervous System - A Radovsky & J Mahler

The Eyes - V Geiss & K Yoshitomi

The Pituitary Gland - J Mahler & MR Elwell

The Adrenal Gland - A Nyska & RR Maronpot

The Thyroid and Parathyroid Glands - JF Hardisty a & GA Boorman

Skin and Subcutis - JC Peckham & K. Heider

Mammary Gland and Specialized Sebaceous Glands (Zymbal, Preputial, Clitoral, Anal) - JC Seely & GA Boorman

Skeletal Muscle - JR Leininger

Bones, Joints, and Synovia - PH Long & JR Leininger

Neoplasm Incidences in B6C3F1 Mice: NTP Historical Data - JK Haseman, MR Elwell & JR Hailey

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Methods in Renal Toxicology
Rudolfs K Zalups Mercer Univ School of Medicine
Lawrence H Lash Wayne State U School/Medicine
Series: Methods in Life Sciences - Toxicology Section  Volume: 1
 

	Presents the only up-to-date compilation of renal methods available in print
	Covers the full spectrum of renal methods - from whole animal and clinical to cellular and molecular approaches
	Contains chapters written by a diverse set of renal investigators, including physiologists, toxicologists, pharmacologists, biochemists and nephrologists
	Provides concise methodological information easily applied in the laboratory
	Includes valuable information useful to renal scientists outside toxicology

The only up-to-date compilation of renal methods available, this book is the definitive resource for any renal researcher eager to stay ahead. Methods in Renal Toxicology presents a vast array of methods for the study of renal cellular and tubular structure, function, and biochemistry under physiological, toxicological, and pathological conditions. It provides detailed descriptions in easy-to-understand language of methods designed to enhance your research efforts.  Methods in Renal Toxicology puts you on the cutting edge with valuable chapters detailing molecular methods and transgene and gene targeting - the most recent approaches to the study of renal toxicology. Overall, the book's topics range from non-invasive assessments of renal function in the whole animal and clinical settings to cellular and molecular approaches. Specifically, the book delves into measurements of clearance and urinary markers, histopathology, and methods to assess renal carcinogenesis, mutagenesis, oxidative stress, mitochondria injury, cellular repair, and drug metabolism and transport. A variety of in vitro methods are also described, including the isolated perfused kidney, micropuncture, microperfusion, microdissection, renal slices, isolated perfused tubules, suspensions of tubules and isolated cells, and primary cell cultures and cell lines.  Methods in Renal Toxicology is a must-have resource for all renal investigators. Nowhere else can you find concise descriptions of traditional and up-to-the-minute renal toxicology methods in such a practical, well-written single-volume guide.

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