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Genetics in
Endocrinology
By John D. Baxter MD, Shlomo Melmed MD, Maria I New MD
784 pp., 198 ills., 04/02
Hardcover
Description
An extensive body of evidence
highlights the crucial importance of endocrine genetics. Examples range from
human growth disorders and obesity to cancers of the prostate and breast. A
pivotal part of the Modern Endocrinology Series, this book presents major
biological studies underlining the significance of data obtained from
knock-out mice, as well as from transgenic animals. Gene therapy and
laboratory evaluation and screening of genetic endocrine diseases are
covered, as are many of the classical endocrine diseases.
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GEN-END
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Genetics in
Endocrinology
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$220.00/Each
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Systematic Approach to the Evaluation of Mouse Mutations
By John P Sundberg, The Jackson Laboratory, Bar Harbor, Maine, USA, Dawnalyn
BoggessThe Jackson Laboratory, Bar Harbor, Maine, USA
216 pp., 07/99
Description
Experts from The Jackson Laboratory
and around the world provide practical advice on everything from how to
establish a colony to where to go for specific mutations. Systematic
Approach to Evaluation of Mouse Mutations includes information on medical
photography, grafting procedures, how to map the genes and evaluate the
special biological characteristics of the mice.
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MOU-SYS
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Systematic Approach to
the Evaluation of Mouse Mutations
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$129.95/Ea
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What's
Wrong With My Mouse?
Behavioral Phenotyping of
Transgenic & Knockout Mice
By Jacqueline N. Crawley
352 pp., 03/2000
Hardcover
Description
Transgenic and knockout mutations
provide an important means for understanding gene function, as well as for
developing therapies for genetic diseases. This engaging and informative
book discusses the many advances in the field of transgenic technology that
have enabled researchers to bring about various changes in the mouse genome.
Equal emphasis is given to both the principles of transgenic and knockout
methods and their applications. A clear and concise format provides
researchers with a comprehensive review of the behavioral paradigms
appropriate for analyzing mouse phenotypes.
What s Wrong with My Mouse?
explains the differences between transgenic knockout mice and their
wild-type controls, while providing critical information about gene function
and expression. This volume recognizes that newly identified genes can
provide useful insights into brain functioning, including brain
malfunctioning in disease states. Written by a world-renowned expert in the
field, the material also covers:
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How to
generate a transgenic or knockout mouse |
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functions (open field, holeboard, rotarod, balance, grip, circadian
activity, etc.) |
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Sensory
abilities (olfaction, vision, hearing, taste, touch, nociception)
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Reproductive behavior, social behavior, and emotional behavior |
Researchers in neuroscience,
pharmacology, genetics, developmental biology, and cell biology will all
find this book essential reading.
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MOU-WW
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What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic & Knockout Mice
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$119.95/Ea
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Natural Pathogens of Laboratory Animals
Their Effects on Research
By David G. Baker
397 pp., ills., 07/03
Description
This important new book informs
laboratory animal veterinarians, animal caretakers, research scientists, and
others, how natural pathogens of laboratory animals, many of which cause no
outward signs of disease, can alter host physiology and compromise the
validity of research findings.
This text opens with an historical
perspective on changes in the general awareness of laboratory animal
pathogens and an overview of the important distinction between infection and
disease. Brief descriptions of housing systems for pathogen exclusion or
containment, and of approaches to pathogen surveillance are also provided.
The body of the text presents chapters
on the most common natural pathogens found in a wide variety of laboratory
animals. For each pathogen there is a description of the agent,
epidemiology, clinical signs, pathology, interference with research, and
methods of diagnosis and control. Each description concludes with a
convenient table indicating the organ systems affected.
Natural Pathogens of Laboratory
Animals is an essential resource for everyone working with laboratory
animals.
Key Features
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Only
single source of information on natural pathogens for these animal
species |
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Quick
reference to 158 of the most common infectious agents
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Information of each pathogen is presented in an easy-to-use format
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Provides the reader with current information on all aspects of
infectious disease |
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NP-LA
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Natural Pathogens of
Laboratory Animals
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$119.95/Ea
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Pathobiology of the Aging Rat Vol I & II
Edited
By U Mohr, DL Dungworth, & CC Capen
10/92
Hardcover
Recognized authorities review the
literature on the aging process in laboratory rats. Taking an organ-system
approach, the work covers development, growth, aging, nonneoplastic and
neoplastic age-associated lesions, and changes in susceptibility to toxins
during aging. The material presented provides important baseline information
for scientists involved in long-term toxicity and carcinogenesis testing,
and will be useful to pathologists, toxicologists, and gerontologists.
Volume 1 covers the blood and lymphoid, respiratory, urinary,
cardiovascular, and reproductive systems. Volume 2 covers the nervous system
and special sense organs, endocrine and digestive systems, integumentary
system and mammary gland, musculoskeletal system and soft tissue, and
general aspects.
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PATHO-RAT
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Pathiobiology of the
Aging Mouse Volume I & II
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$325.00/Ea
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Handbook of Pre-Clinical Continuous Intravenous Infusion
By Guy Healing, David Smith
352 pp., 10/2000
Description
This book is about the
practice of infusing experimental animals with test substances
efficiently and humanely. There has never before been one manual on this
subject - often researchers have to look through many different sources
to get this information. Any toxicologist or pharmacologist involved in
pre-clinical drug studies will find this book valuable.
Table of Contents
- Introduction D. Smith and
G. Healing
- Femoral Cannulation Using the Jacket/Harness Model in the Rat O.
Green and D. Patten
- Femoral Cannulation Using the Tail Cuff Exteriorisation Method in the
Rat A. McCarthy
- Tethering and the Implanted Button Model in the Rat E. Miedel
- Multidose Infusion Toxicity Studies in the Rat G. Healing
- Reproductive Infusion Toxicity Studies in the Rat P. Barrow
- Femoral Cannulation Using the Tail Cuff Model in the Mouse H. Van
Wijk and D. Robb
- Multidose Infusion Toxicity Studies in the Mouse H. Van Wijk and D.
Robb
- Jugular Cannulation and Efficacy Studies in the Mouse I. Horii
- Femoral Cannulation of the Rabbit for Reproductive Toxicity Studies
C. Copeman and K. Robinson
- Jugular Cannulation of the Rabbit for Reproductive Toxicity Studies
E. Gordon and S. Lynch
- Jugular Cannulation of the Dog N. Pickersgill
- The Non-Ambulatory Model in Dog Multidose Infusion Toxicity Studies
N. Pickersgill
- The Ambulatory Model in Dog Multidose Infusion Toxicity Studies T.R.
Gleason and C. Chengelis
- Surgical Preparation of the Large Primate V. Mendenhall, S. Cornell
and M. Scalaro
- Multidose Infusion Toxicity Studies in the Large Primate M. Walker
- Surgical Preparation and Multidose Infusion Toxicity Studies in the
Marmoset C. Schnell
- Surgical Preparation of the Mini-Pig P. Brinck
- Multidose Infusion Toxicity Studies in the Mini-Pig P. Brinck
- Reproductive Toxicity Studies in the Mini-Pig P. McAnulty
- Common Pathological Findings in Continuous Infusion Studies J. Evans
and P. Kerry
- The Use of Mini-Osmotic Pumps in Continuous Infusion Studies L.
Perkins, C. Peer and P. Murphy-Hackley
- The Contribution of Vehicles, Rates of Administration and Volumes to
Infusion Studies K. Hickling and D. Smith
- Equipment for Continuous Intravenous Infusion A. Jacobson
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PRE-CLIN
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Handbook of Pre-Clinical
Continous Intravenous Infusion
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$159.95/Ea
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