Wheaton Science Products has long been an innovator in cell culture flasks. The Wheaton Magna Flex® impeller produces high-yield cultures by maintaining even circulation while keep­ing cultures in suspension. Slow acceleration and slow stop from the Wheaton Micro-Stir® stirrer prevent cell detachment from micro-carriers.

Wheaton also invented an adjustable impeller flask that does not have a rod extending through the top of a flask. Celstir flasks feature adjustable blade impeller for increased aeration and dimpled bottom to prevent the accumulation of cells under the impeller.*

When used with the Micro-Stir, which can operate at very low speeds, the Celstir flask provides an optimum environment for most suspension lines, including insect cell cultures. Hybridomas and adapted cell lines can also be grown in these spinner flasks. '­Sidearms on Magna Flex and Celstir vessels 500 mL and larger were widened to accommodate monitoring and control devices or media inlet/outlet lines. Wheaton has now moved cell culture another step forward with its innovative patented MantaRay° single-use culture flask. The MantaRay®  comes pre-sterilized to protect cell cultures. The MantaRay® has a unique impeller that provides efficient, gentle stirring for both suspension or micro-carrier culture. The MantaRay® is disposable; discard it after use and save the time, trouble and expense of autoclaving and cleaning.                                                  
                                                                                                                                                                *dimpled bottom on the 125mL size and larger
 

• Single use spinner flask with integrated magnet

• Pre-sterilized making it ready to use out of the box

• Break resistant unit has less potential for culture/sample loss

• One MantaRay generates the same yield as 77 T175 T-flasks conserving on valuable incubator space and reducing costs associated with laboratory consumables

The MantaRay's integrated paddle spinner system is optimized for culturing volumes of 500 mL through 1000 mL. Using a vertically oriented stirrer, the MantaRay® ensures that cells are evenly distributed throughout the entire volume of culture.

Unlike conventional spinner flasks, the MantaRay's paddle system comes ready-to-use, eliminating the need for assembly and disassembly of the device.  The unique design of the spinner allows for even distribution of nutrients and oxygen; thus creating uniform media conditions for cell propagation. The constant agitation caused by the paddle system also prevents cells from settling to the bottom and adhering to the side walls.

The paddle is integrated with the top plate, which stabilizes the fixed stirrer height thus eliminating validation concerns due to height adjustments. The paddle and bag are heat sealed to the top plate reducing potential contamination related to adhesive compounds. The only required pieces of equipment for use of the MantaRay® system are the MantaRay® and a magnetic stirrer. 
 

• Impeller rod does not protrude up through top cap

• Sidearms for 500 mL - 8 L flask allow vented caps which enables the flask to "breathe" while protecting from contamination.

• 1:1 headspace for good gas exchange

• No contamination from stirring rod

• Completely autoclavable

• Water jacket allows for precise temperature control

• Manufactured from Wheaton 33 low extractable borosilicate glass

• Proportioned to provide a head space ratio of 1:1 or greater

• The impeller does not protrude through the top cap

• Fully autoclavable

• PTFE faced rubber-lined caps on sidearms

The Double-Sidearm Celstir with water jacket allows precise temperature control of its contents when operated with a recirculating water bath. The hose connectors accept 1/4 in 16.35 mm) ID tubing. This unit is made from Wheaton 33 low extractable borosilicate glass that conforms to USP Type I and ASTM E-438 Type I, Class A requirements. The 500 and 1000 mL sizes can also be used with Wheaton Vented Cap Cat. No. W240751.

• Designed for use with microcarrier cultures

• Sidearms for 500 mL - 6 mL flasks allow vented caps which enables the flask to "breath" while protecting from contamination

• Gentle, even stirring action

The Wheaton Magna Flex Spinner Flasks feature a flex-type, bulb-shaped glass impeller that rotates from a fixed position above liquid level around an indentation in the base of the flask. Primarily designed for use with microcarrier cultures, this unique stirring system increases stirring efficiency and provides a gentle, even circulation throughout the flask while keeping the beads in suspension.  All flasks have been proportioned to provide a head space ratio of 1:1 or greater. A removable stainless steel pin immobilizes the impeller during handling or decanting to prevent damage to cells or microcarriers. Sizes 500 mL and larger can accommodate the Wheaton Vented Cap (Cat. No. W240751).